复方甘草酸苷治疗儿童过敏性紫癜临床疗效观察

Effect Observation of Compound Glycyrrhizin in the Treatment of Anaphylactoid Purpura of Children

目的观察联用复方甘草酸治疗儿童过敏性紫癜的临床疗效。方法 80例过敏性紫癜患儿随机分为两组,对照组40例,治疗组40例。对照组给予基础治疗及常规激素治疗,治疗组在基础治疗上联用复方甘草酸苷注射液,治疗一周后比较两组疗效。结果治疗组总有效率92.5%,明显优于对照组72.5%(P<0.05)。结论联用复方甘草酸苷治疗过敏性紫癜疗效较传统激素方法效果好,并且安全、副作用小,值得临床推广应用。

Objective To observe the curative effect of compound glycyrrhizin for anaphylactoid purpura of children. Methods 80 children with anaphylactoid purpura were randomly divided into the control group （n = 40） and the treatment group （n = 40）. The control group received the basic treatment and conventional hormone therapy, while the treatment group received the compound glycyrrhizin injection in addition to the treatment in the control group. The curative effects between two groups were compared 1 week after the treatment. Results The total effective rate in the treatment group was 92.5%, which was significantly better than that in the control group （72.5%）, P 〈0.05. Conclusions Compound glycyrrhizin has better effect in treating anaphylactoid purpura of children compared with the traditional hormone method, which is worthy of clinical application.