期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

巨噬细胞移动抑制因子与急性冠脉综合征的研究进展 被引量：2

下载PDF
导出
摘要 研究表明，炎症反应是引发心血管疾病的重要因素，炎症反应可能参与了急性冠脉综合征（acute coronary syndrome，ACS）发生、发展的全过程[1]。巨噬细胞移动抑制因子（macrophage migration inhibitory factor，MIF）是具有多种生物活性的重要细胞因子，参与一系列炎症过程，在动脉粥样硬化（atherosclerosis，AS）的形成、发展及斑块破裂过程中起到重要作用[2]。为此，本文将对MIF与ACS的研究现状作一综述。
作者 郭俊林 杨毅宁
机构地区 新疆医科大学第一附属医院心脏中心
出处 《中国循证心血管医学杂志》 2012年第2期170-171,173,共3页 Chinese Journal of Evidence-Based Cardiovascular Medicine
基金 新疆维吾尔自治区自然科学基金(2010211A44)
关键词 巨噬细胞移动抑制因子 急性冠脉综合征 动脉粥样硬化 炎症反应 心血管疾病 细胞因子 生物活性 炎症过程
分类号 R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献26

  • 1Hansson GK,Libby P.The immune response in atherosclerosis:a double edged sword[J].Nat Rev Immunol,2006,6(7):508-519.
  • 2Takahashi M,Nishihira J,Shimpo M.Macrophage migration inhibitory factor as a redox sensitive cytokine in cardiac myocytes[J].N American J Cardiovascular Research,2001,52(3):438-445.
  • 3Bloom BR,Bennett B.Mechanism of a reaction in vitro associated with delayed-type hypersensitivity[J].Science,1966,153(731):80-82.
  • 4Bernhagen J,Calandra T,Mitchell RA,Martin SB,Tracey KJ,Voelter W,et al.MIF is a pituitaryderived cytokine that potentiates lethal endotoxaemia.Nature.1993,365(6448):756-9.
  • 5Calandra T,Roger T.Macrophage migration inhibitory factor:a regulator of innate immunity[J].Nat Rev Immunol,2003,13(10):791-800.
  • 6Flaster H,Bernhagen J,Calandra T,et al.The macrophage migration inhibitory factor-glucocorticoid dyad:regulation of inflammation and immunity[J].Mol Endocrinol,2007,21(6):1267-1280.
  • 7Mirzaei K,Hossein-Nezhad A,Aslani S,et al.Energy Expenditure Regulation Via Macrophage Migration Inhibitory Factor (MIF) in Obesity and In Vitro Anti-MIF Effect of Alpinia Officinarum Hance Extraction[J].Endocr Pract,2011,(29):1-28.
  • 8Kleemann R,Zadelaar S,Kooistra T.Cytokines and atherosclerosis:a comprehensive review of studies in mice[J].Cardiovasc Res,2008,79(3):360-376.
  • 9CalandraT,RogerT.Marophage migration inhibitory factor:Aregulator of Innate immunity[J].Nat Revllnlllunol,2003,3(10):791-800.
  • 10Burger-Kentischera A,Gobel H,Kleemann R,et al.Reduction of the aortic in ammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF)[J].Atherosclerosis,2006,184(1):28-38.

二级参考文献16

  • 1Lusis AJ. Atherosclerosis[J]. Nature, 2000, 407(6801): 233-241.
  • 2Jialal I, Devara JS. The role of oxidized low density lipoprotein in atherogenesis[J]. Nutrition, 1996, 126(8): 1053s-1057s.
  • 3Yang Y, Mundt SS, Ayaala JM, et al. Identification of macrophage migration inhibitory factor as a potent endothelial cells growth-promoting agent released by ectopic human endometrial cells[J]. Clin Endocrinol Metab, 2000, 85(3): 4721-4727.
  • 4Burger KA, Goebel H, Seiler R, et al. Expression of macrophage migration inhibitory factor in different stages of human atherosclerosis[J]. Circulation, 2002, 105(13): 1561-1566.
  • 5Meyer SK. Macrophage migration inhibitory factor increases MMP-2 activity in DU-145 prostate cells[J]. Cytokine, 2000, 12(7): 914-921.
  • 6Stamps SL, Taylor AB, Wang SC, et al. Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants[J]. Biochemistry, 2000, 39(32): 9671-9678.
  • 7Kamimura A, Kamachi M, Nishihira J, et al. Intracellular distribution of macrophage migration inhibitory factor predicts the prognosis of patients with adenocarcinoma of the lung[J]. Cancer, 2000, 89(2): 334-341.
  • 8Kitaichi N, Ogasawara K, Iwabuchi K, et al. Different influence of macrophage migration inhibitory factor (MIF) in signal transduction pathway of various T cell subsets[J]. Immunobiology, 2000, 201(3-4): 356-367.
  • 9Ross R. Atherosclerosis-AN inflammatory disease[J]. N Engl J Med, 1999, 340(2): 115-126.
  • 10Swpoe MD, Lolis E. Macrophage migration inhibitory factor: Cytokine, hormone or enzyme [J]. Rev physiol Biochem Pharmacol, 1999, 139(11): 1-32.

共引文献166

同被引文献27

  • 1Ley K,Miller YI,Hedrick CC.Monocyte and macrophagedynamics during atherogenesis[J].Arterioscler ThronihVasc Biol,2011,31(7):I 506-516.
  • 2Lawrence T,Natoli G.Transcriptional regulation of macro-phage polarization:enabling diversity with identity[J].NatRev Immunol,2011,11(11):750-761.
  • 3Mantovani A,Garlanda C,Locati M.Macrophage diversityand polarization in atherosclerosis:a question of balance[J].Arterioscler Thromb Vasc Biol,2009,29(10):I419423.
  • 4Gupta H,Dai L,Datta G,et al.Inhibition of Iipopolysac-charide-induced inflammatory responses by an apolipopro-tein Al mimetic peptide[J].Circ Res,2005,97(3):236-243.
  • 5Wilson HM.Macrophages heterogeneity in atherosclerosis-implications for therapy[J].J Cell Mol Med,2010,14(8):2 055-065.
  • 6Liu C,Li Y,Yu J,et al.Targeting the shift from Ml toM2 macrophages in experimental autoimmune encephalomy-elitis mice treated with fasudil[J].PLoS One,2013,8(2):e54 841.
  • 7Shil AB.Termination of atherothrombosis intervention inmetabolic syndrome with low high-density lipoprotein cho-lesterol and high triglycerides:impact on global healthstudy and decision to use extended-release niacin in elderly[J].J Am Geriatr Soc,2011,59(12):2 397-398.
  • 8Kim KD,Lim HY,Lee HG,et al.Apolipoprotein A-I in-duces IL-IO and PGE2 production in human monocytesand inhibits dendritic cell differentiation and maturation[J].Biochem Biophys Res Commun,2005,338(2):I126-136.
  • 9Sica A,Mantovani A.Macrophage plasticity and polariza-tion ;in vivo veritas[J].J Clin Invest,2012,122(3):787-795.
  • 10Orr JS,Puglisi MJ,Ellacott KL,et al.Toll-like receptor4 deficiency promotes the alternative activation of adiposetissue macrophages[J].Diabetes,2012,61(11):2718-727.

引证文献2

二级引证文献11

中国循证心血管医学杂志
2012年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部