环氧树脂厂工人双酚A接触水平调查

Exposure Levels of Bisphenol A among Workers in A Resin Factory

[目的]评估树脂厂工人双酚A接触水平,为下一步建立剂量反应关系作基础。[方法]2010年选择某树脂厂,在对现场生产工艺流程、设备等的调查基础上,进行定点及个体空气采样,并收集154名工人班前尿及班后尿,酶解检测总双酚A水平;另收集当地无明确双酚A源水厂的109名工人尿样作为生物监测的对照组。[结果]树脂厂96.5%的空气样品测出双酚A。树脂厂工人班前尿与班后尿肌酐校正总双酚A水平中位数分别为11.31、16.17μg/g,班后尿水平高于班前尿水平(P<0.05)。对照组肌酐校正水平中位数分别为2.96、2.56μg/g,明显低于树脂厂工人的检测值(P<0.001),其单侧95%上限分别为19.05、28.84μg/g。[结论]树脂厂工人双酚A接触水平高,有必要采取措施控制接触水平。

[ Objective ] To assess bisphenol A （BPA） exposure levels of workers and to provide basis for studying its doseresponse correlation. [ Methods ] In 2010, local and personal airborne samples were taken in a resin factory. Spot urine samples of 154 workers from the resin factory and 109 workers from a control factory were collected before and after shifts to measure total BPA. [ Results ] In the resin factory, 96.5% of the air samples were BPA detectable; the medians of creatinine-adjusted urinary BPA levels preand post-shift were 11.31 and 16.17 μg/g respectively, and the urinary BAP levels of post-shift was significantly higher than that of pre-shift （P〈 0.05）. In the control factory, the medians of creatinine-adjusted urinary BPA levels were 2.96 and 2.56 μg/g respectively, which was significantly lower than those in the resin factory （P〈 0.001）, and one-side 95% upper bounds were 19.05 and 28.84μg/g, respectively. [ Conclusion ] Workers from the resin factory are occupationally exposed to BPA at a high level. It is necessary to control the occupational exposure level of BPA.