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经鼻间歇正压通气治疗新生儿呼吸窘迫综合征的疗效观察 被引量：9

Effects of nasal intermittent positive pressure ventilation in treatment for neonates respiratory distress syndrome
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摘要 目的:观察经鼻间歇正压通气(NIPPV)在新生儿呼吸窘迫综合征(NRDS)中的应用效果。方法:将48例NRDS患儿随机分为NIPPV组(25例)和经鼻持续气道正压通气(NCPAP)组(23例),观察比较2组治疗的成功率、治疗的时间、治疗前后动脉血气变化、氧合指数及并发症。结果:NIPPV组治疗成功率为72.0%,高于NCPAP组的43.5%(P<0.05),NIPPV组治疗后1 h的动脉氧分压、氧合指数的升高显著大于NCPAP组(P<0.05)。结论:NIPPV作为初始通气模式治疗NRDS是可行的,且疗效优于NCPAP。 Objective ：To evaluate the effects of nasal intermittent positive pressure ventilation （NIPPV） in treatment for neonates respiratory distress syndrome（NRDS）. Methods：Forty-eight neonates with NRDS were randomly divided into NIPPV group（25 cases） and nasal continuous positive airway pressure （NCPAP） group （23 cases）. The success rates, treatment time, the changes of arterial blood gas before and after treatment, oxygen index and complications of two groups were observed. Results：The treatment success rates of NIPPV group （ 72.0% ） were higher than NCPAP group （43.5 % ） （ P 〈 0.05 ）. The arterial oxygen partial pressure oxygen and index of NIPPV group were significantly higher than that of NCPAP group at 1 hour after treatment. Conclusions： The treatment for NRDS with NIPPV is feasible, and the effects of NIPPV on NRDS are better than NCPAP.
作者 陈信 潘家华 丁周志 徐兵 夏群
机构地区 安徽医科大学附属省立医院儿科 蚌埠医学院第一附属医院儿科
出处 《蚌埠医学院学报》 CAS 2012年第5期541-543,547,共4页 Journal of Bengbu Medical College
关键词 呼吸窘迫综合征 婴儿 新生 疾病 经鼻间歇正压通气 持续气道正压通气 respiratory distress syndrome infant, newborn, diseases nasal intermittent positive pressure ventilation nasal continuous positive airway pressure
分类号 R722.12 [医药卫生—儿科]
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参考文献19

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二级参考文献17

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共引文献119

同被引文献39

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  • 2周小坚,陈鲜威,陈均亚,陆中权.极低体重儿在撤机后应用经鼻同步间歇指令通气对呼吸支持的评估[J].临床儿科杂志,2005,23(1):47-48. 被引量：2
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引证文献9

二级引证文献37

蚌埠医学院学报
2012年 第5期

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