CT指导下急性脑梗死患者的静脉溶栓治疗

Intravenous thrombolytic therapy in patients with acute cerebral infarction under CT guidance

目的探讨头颅CT指导下静脉尿激酶溶栓治疗急性脑梗死的临床效果。方法两组患者各60例均常规进行原发病的对症治疗,低分子肝素静注,阿司匹林口服,研究组患者在此基础上,加用CT指导下尿激酶静脉溶栓治疗。结果治疗前两组患者神经功能缺损评分差异无统计学意义(P>0.05),治疗后两组评分均有明显下降(P<0.05),研究组患者治疗后神经功能缺损评分明显低于对照组(P<0.05)。研究组患者治疗总有效率明显高于对照组,数据经统计学比较差异有统计学意义(P<0.05)。结论 CT指导下行尿激酶静脉溶栓治疗急性脑梗死具有较好疗效,可有效改善患者神经功能缺损情况,改善血液动力学,提高患者生活质量。

Objective To discuss the clinical effects of intravenous urokinase thrombolysis therapy in patients with acute cerebral infarction under CT guidance, Methods 60 cases each in two groups were all traditionally treated with symptomatic and intravenous injected with low molecular weight heparin. Study group were treated by intravenous thrombolytic therapy under CT scan. Results The neurological deficit score of two groups had no significant difference before treatment （P 〉 0. 05）, and the score had significantly reduced after treatment （P 〈 0. 05 ）, study group was lower than control group （P 〈 0. 05）. The total effec- tive rate was significantly higher than control group （P 〈 0. 05 ）. Conclusion It has good effects of intravenous urokinase throm- bolysis therapy in patients with acute cerebral infarction under CT guidance, which can improve the neurologic impairment and hemodynamic, and improve the quality of life of patients.