束缚应激引起小鼠脾内TrkC mRNA水平变化
摘要
用地高辛标记的寡核苷酸探针进行RNA缝隙杂交,观察了束缚应激不同阶段的BALB/c小鼠脾内TrkC mRNA表达水平的变化。结果显示脾内TrkC mRNA于应激8h时表达明显增加,而于4和12h时均有不同程度的降低。提示NT-3/TrkC系统在应激引起的神经-免疫系统相互调节中起一定作用。
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