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7-羟基-3,4-二氢-2(1H)-喹啉酮的新合成方法研究 被引量：2

A New Method for Synthesis of 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
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摘要 以间甲氧基苯胺和肉桂酰氯为原料,经N-酰化、分子内傅-克烃化和还原反应合成了7-羟基-3,4-二氢-2(1H)-喹啉酮。此方法反应条件较温和,合成的目标产物产率较高,总收率达63%。各步产物结构经IR、1H NMR等表征。 7-Hydroxy-3,4-dihydro-2（1H）-quinlinone was synthesized from 3-methoxyaniline and cinnamoyl chlorid via three-step reaction in 63% over all yields.The structure of the productsin each step were characterized by 1H NMR and IR spectra.
作者 周伟军
机构地区 浙江工业大学
出处 《广州化工》 CAS 2012年第10期89-89,97,共2页 GuangZhou Chemical Industry
关键词 7-羟基-3 4-二氢-2(1H)-喹啉酮 7-羟基-2(1H)-喹啉酮 间甲氧基苯胺 肉桂酰氯 7-hydroxy-3 4-dihydro-2（1H）-quinlinone 7-hydroxy-2（1H）-quinlinone 3-methoxyaniline cinnamoyl chlorid
分类号 TQ463.5 [化学工程—制药化工]
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参考文献6

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二级参考文献38

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广州化工
2012年 第10期

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