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登革病毒重组包膜蛋白表达及其应用的研究进展 被引量：2

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摘要 登革病毒（dengue virus,DV）是当前严重影响人类健康的虫媒传播病毒,无特效的疫苗和药物。目前在DV的诊断、疫苗的研发以及对抗体依赖性增强效应（ADE效应）机制的研究上,DV包膜蛋白越来越受到人们的关注。研究人员通过不同的载体表达不同形式的DV包膜蛋白,对研究目的以及研究结果的应用有着巨大的影响。本文主要就DV包膜蛋白在不同表达系统中的表达方式进行综述,
作者 郭勇晖
机构地区 南方医科大学珠江医院检验医学部临床医学实验中心
出处 《广东医学》 CAS CSCD 北大核心 2012年第9期1350-1352,共3页 Guangdong Medical Journal
关键词 膜蛋白表达 病毒重组 应用 包膜蛋白 抗体依赖性 登革病毒 传播病毒 人类健康
分类号 R739.63 [医药卫生—肿瘤]
  • 相关文献

参考文献26

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二级参考文献15

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共引文献7

同被引文献14

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  • 4Li XQ, Qiu LW, Chert Y, et al. Dengue virus envelope domain Ⅲ immunization elicits predominantly cross-reactive, poorly neu-tralizing antibodies localized to the AB loop: implications for den- gue vaccine design[J]. J Gen Virol, 2013, 94(Pt 10): 2191- 2201.
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  • 9林华,杨会强,李竹石,杨健,赵宇,刘俐,葛永红,曾献武,曹毅,乔代蓉,李玉华.登革病毒3型E蛋白的原核表达及抗体的制备[J].中华微生物学和免疫学杂志,2013,33(5):371-374. 被引量：2
  • 10汪伟,丁显平,杨会强,李竹石,谭帅,赵宇,刘莉娜,谭昌耀,曾献武.登革病毒1型E蛋白的原核细胞表达及多克隆抗体的制备[J].国际检验医学杂志,2013,34(23):3107-3109. 被引量：1

引证文献2

广东医学
2012年 第9期

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