摘要
目的：探讨超氧化物岐化酶（SOD），微量元素锌（Zn）、铜（Cu）、铁（Fe）水平与白癜风病人发病进程的相关关系。方法：正常人及白癜风病人血SOD活性测定采用邻苯三酚自氧化法。血清Zn、Cu、Fe含量测定采用原子吸收火焰法。结果：经统计学处理，病人血SOD活性，血清Zn明显低于对照组，Fe明显高于对照组（P〈0．01），有显著性差异，Cu与对照组相比无显著性差异（P〈0．05）。结论：SOD、Zn、Cu、Fe在白癜风病人的发病进程中互相起协调与拈抗作用，其在发病机理及治疗中可提供一定的依据。
Objective： This investigation of clinical epidemiology was to explore the relationship be- tween vitiligo incidence and the level of SOD and trac elements such as Zn,Cu,Fe. Methods The level of Zn,Cu ,Fe in the serum was determined atomic absorption spectropotometer ,and the level of SOD was de- termined by method. Results The level of Zn and SOD in patients was obviously lower than that of the contrast group, the level of Fe in patients was obviously higher than that of the contrast group. There was a significant difference between the two groups, （P 〈 0.01）.And there was no significant difference be- tween the two groups in the level of serum Cu. Conclusion The level of SOD and trace elements such as Zn Fe in vitiligo patients were obviously different from the level in the contrast group ,it suggested that the difference between the two groups have a close relation to incidence and restoration of vitiligo.
