茵栀黄注射液保留灌肠治疗新生儿病理性黄疸疗效观察

Clinical observation on treating neonatal jaundice retention enema with the Yin Zhi Huang injection

目的:观察茵栀黄注射液保留灌肠治疗新生儿病理性黄疸的临床疗效。方法:将收治的新生儿病理性黄疸180例随机分为对照组90例和观察组90例,对照组给予间断光疗、酶诱导剂、白蛋白、纠酸等治疗措施;观察组在此基础上给予温热的茵栀黄注射液保留灌肠。比较两组患儿胆红素值、胎粪排净时间、光疗时间及喂养耐受情况。结果:观察组患儿较对照组胆红素值明显降低,胎粪排净时间及光疗时间明显缩短,喂养耐受性更高,(P<0.05或P<0.01),无不良反应。结论:茵栀黄注射液保留灌肠治疗新生儿病理性黄疸疗效显著,值得临床推广使用。

Objective： To observe the clinical efficacy of treating neonatal jaundice retention enema the with the Yin Zhi Huang injection. Methods： 180 cases of neonatal jaundice were randomly divided into control group and observation group, 90 each, the control group received intermittent light therapy, enzyme inducers, albumin, correct acid treatment; the observation group on this basis was given the warm Yin Zhi Huang injection by retention enema. Two groups were compared the difference in bilirubin, meconium clean time, the time of phototherapy and feeding tolerance. Results： Bilirubin value of the observation group compared with the control group was significantly lower, meconium net time and phototherapy was significantly shorter, feeding tolerance higher （P〈0.05 or P〈0.01）, no adverse reactions. Conclusions： The Yin Zhi Huang injection on treating the neonatal pathologic jaundice by retention enema have a significant effect and are worthy of clinical application.