经导管动脉化疗栓塞后联合CT引导射频消融肝癌的初步应用

Initial application of combination therapy of percutaneous radiofrequency ablation and transcatheter arterial chemoembolization in primary hepatic carcinoma

目的探讨经导管动脉化疗栓塞(TALE)后联合CT引导射频消融(RFA)治疗肝癌的治疗效果并探讨相关介入技术。方法 14例肝癌患者共21个病灶,Child-Pugh分级A级或B级,分别TACE联合CT引导下(RFA)治疗,治疗术前术后均行CT、MRI等影像学检查,并定期随访21个月。结果 14例患者21个病灶的联合治疗均取得了成功,术后发热,局部疼痛和暂时性肝功能异常是常见的并发症,对症适当干预后缓解,所有病例均未出现严重并发症。结论 CT引导下经皮射频消融可与TACE联合应用,使肿瘤完全坏死,有助于提高对肝癌的治疗效果。

Objective To investigate the clinical effect and：Interventional fechnology of a combination therapy of percutaneous radiofrequency ablation （RFA） and transcatheter arterial chemoembolization（TACE） in primary hepatic carcinoma. Methods 14 cases of primary hepatic carcinoma patients of Child-Pugh grade A or B with total of 21 lesions underwent TACE combined with CT-guided RFA treatment, preoperative and postoperative CT,MRI imaging were studied with follow-up 20 months. Results All patients were treated with combination therapy successfully Postoperative fever, local pain and transient liver dysfunction was the common Phenomenon without serious complications. Conclusion Transcatheter arterial chemoembolization （TACE） combined with percutaneous radiofrequency ablation （RFA）in primary hepatic carcinoma could improve the treatment.