期刊文献+

肿瘤抑制因子microRNA126的研究进展 被引量:1

原文传递
导出
摘要 大量研究表明,microRNA作为一种重要的转录后基因调控元件,在多种疾病尤其是肿瘤的发生发展中发挥重要作用。microRNA126被认为是一种肿瘤抑制因子,在多种肿瘤如胃癌、结肠癌、肺癌、宫颈癌以及乳腺癌等肿瘤中有明显的抑制作用。此外microRNA126在其他疾病如哮喘、血管炎症等也有着重要作用。本文对microRNA126的最新研究进展作一综述。
出处 《中华消化病与影像杂志(电子版)》 2011年第1期50-54,共5页 Chinese Journal of Digestion and Medical Imageology(Electronic Edition)
  • 相关文献

参考文献10

  • 1Runhua Feng,Xuehua Chen,Yingyan Yu,Liping Su,Beiqin Yu,Jianfang Li,Qu Cai,Min Yan,Bingya Liu,Zhenggang Zhu.miR-126 functions as a tumour suppressor in human gastric cancer[J].Cancer Letters.2010(1)
  • 2Yanqin Sun,Yifeng Bai,Fan Zhang,Yu Wang,Ying Guo,Linlang Guo.miR-126 inhibits non-small cell lung cancer cells proliferation by targeting EGFL7[J].Biochemical and Biophysical Research Communications.2009(3)
  • 3Vivien Wang,Wei Wu.MicroRNA-Based Therapeutics for Cancer[J].BioDrugs.2009(1)
  • 4Bo Liu,Xiao-Chun Peng,Xiao-Li Zheng,Jun Wang,Yong-Wen Qin.MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo[J].Lung Cancer.2009(2)
  • 5ChunguangGuo,Jerome F.Sah,LydiaBeard,James K. V.Willson,Sanford D.Markowitz,KishoreGuda.The noncoding RNA, miR‐126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3‐kinase signaling and is frequently lost in colon cancers[J].Genes Chromosom Cancer.2008(11)
  • 6M. Crawford,E. Brawner,K. Batte,L. Yu,M.G. Hunter,G.A. Otterson,G. Nuovo,C.B. Marsh,S.P. Nana-Sinkam.MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines[J].Biochemical and Biophysical Research Communications.2008(4)
  • 7Takashi Seto,Masahiko Higashiyama,Hiroko Funai,Fumio Imamura,Kazutsugu Uematsu,Nobuhiko Seki,Kenji Eguchi,Takeharu Yamanaka,Yukito Ichinose.Prognostic value of expression of vascular endothelial growth factor and its flt-1 and KDR receptors in stage I non-small-cell lung cancer[J].Lung Cancer.2006(1)
  • 8Eckart Laack,Antje Scheffler,Iris Burkholder,Ina Boeters,Birte Andritzky,Gunter Schuch,Michael G?rn,Gaby Vohwinkel,Lutz Edler,Walter Fiedler,Dieter Kurt Hossfeld.Pretreatment vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) serum levels in patients with metastatic non-small cell lung cancer (NSCLC)[J].Lung Cancer.2005(1)
  • 9M. Osaki,M. Oshimura,H. Ito.PI3K-Akt pathway: Its functions and alterations in human cancer[J].APOPTOSIS.2004(6)
  • 10David P Bartel.MicroRNAs[J].Cell.2004(2)

同被引文献12

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部