血小板平均容积与经皮冠状动脉介入术后患者冠状动脉支架内血栓形成的相关性

The relationship between the mean platelet volume and the rate of ocuration of sub-acute thrombosis in patients after PCI

目的观察血小板平均容积与行经皮冠状动脉介入术（PCI）后患者冠状动脉支架内血栓（ST）形成的关系，确定观察PCI术后患者血栓形成的一个简明的高危指标。方法对229例PCI术后患者测定血小板平均容积（MPV），MPV显著增大的患者为观察组，MPV正常的患者为对照组。观察两组患者ST情况，进行对比分析。结果对照组ST发生率为1．22％，低于观察组的6．15％（X2=4．02，P〈0．05）。结论MPV增大是PCI术后患者血栓形成的高危因素，及时有效的调整抗栓治疗方案，对预防PCI术后ST发生有重要临床意义。

Objective To observe the relationship between the mean platelet volume （MPV） and stent thrombosis（ST） in patients after percutaneous coronary interventional procedures （PCI）, to determine a concise and high-risk indicator to predict thrombosis in the patients after PCI. Methods To determine the MPV from 229 patients after PCI. The patients with MPV significantly increased were sekected as the observation group, the patients with normal MPV were selected as the control group. The stsituation in the two groups of ST was observed. The values in the two grups were analyzed. Results The ST rate of control group was 1.22%, which was lower than that of the observation group （6.15 % ） （ X2 = 4.02, P 〈 0.05 ）. Conclusion The value of MPV increased was a risk factor for patients with thrombosis after PCI. Taking effective and timely adjustment of antithrombotic treatment options had an important clinical significance to prevent ST occur in patients after PCI.