小梁切除术联合丝裂霉素C及青光眼引流器植入治疗青光眼的疗效评价

The evaluation of therapeutic efficiency in glaucoma treated by trabeculectomy with mitomycin C (MMC) and glaucoma shunting device implantation

目的评价小梁切除术联合丝裂霉素C及青光眼引流器植入治疗青光眼的近期疗效。方法 25眼(20例)青光眼患者行小梁切除术联合丝裂霉素C及青光眼引流器植入术,随访6个月,观察术后最佳矫正视力、眼压、滤过泡形态、眼底、视野、术后前房深度及并发症情况。结果 25眼(20例)术后平均眼压(11.42±2.14)mmHg,眼压在6～21 mmHg者23眼,眼压控制成功率为92.0%;最佳矫正视力提高15眼(60.0%),术后功能性滤过泡24眼(96.0%),6眼(24.0%)发生浅前房,1眼出现(4.0%)前房出血,2眼(8.0%)脉络膜脱离,眼底及视野未出现明显变化。结论小梁切除术联合丝裂霉素C及青光眼引流器植入能有效降低青光眼患者眼压,促进功能性滤过泡形成,从而提高青光眼的手术成功率。

Objective To evaluate the short therapeutic effect of treating glaucoma by trabeculectomy combined with mitomycin C（MMC）and glaucoma shunting device implantation.Methods Trabeculectomy with MMC and glaucoma shunting device implantation were used to treat 25 eyes of 20 patients with glaucoma.After the operation the best corrected visual acuity（BCVA）,intraocular pressure（IOP）,shape of filtration bleb,fundus,perimetry depth of anterior chamber and complication were observed six month.Results After operation the mean IOP of 25 eyes was（11.42±2.14）mmHg and 23eyes were between 6~ 21 mmHg,The curative rate was 92.0 %,BCVA improved in 15 eye（60.0%）,and functionality filtration blebs were formed in 24 eyes（96.0%）,shallow anterior chamber occurred in 6 eyes（24.0%）,hyphema in one eye（4.0%）and choroidal detachment in 2 eyes（8.0%）.Fundus and perimetry did not change obviously.Conclusion The trabeculectomy combined MMC and glaucoma shunting device implantation can reduce IOP of glaucoma effectively,promote the formation of functionality filtration bleb,and then improve the success rate of glaucoma surgery.