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食管癌常规放疗与三维适形放疗剂量学对比分析 被引量:4

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摘要 目的比较中晚期食管癌三维适形放疗和常规放疗靶区剂量、正常组织受量、适形指数的差异。方法25例中晚期食管癌病例,应用放射治疗计划系统(TPS)分别设计2种照射技术,即三维适形放疗(A)和模拟常规放疗(B),比较同一处方剂量(66Gy)靶区计划靶区体积(PTV)最大值(Dmax)、最小值(Dmin)、平均值(Dmean)、适形指数(CI);双肺V20V30Dmean、心脏V40Dmean。结果PrrV参数:A、B两组Dmax分别为62.90Cy和68.49Gy两者比较差异无统计学意义(t=-0.11,P〉0.05);A与B的Dmin、Dmean、CI分别是56.70和27.36Cy、63.65和60.88Gy,0.63和0.47,差异有统计学意义(均P〈0.05)。危及器官:双肺V20V30DmeanA均高于B,差异有统计学意义(均P〈0.05);心脏V40、DmeanA低于B,差异有统计学意义(均P〈0.05)。结论三维适形放疗相对常规放疗技术的靶区剂量分布更理想,对降低心脏受照射量有一定优势。肺的受照射量可能增加。
出处 《肿瘤研究与临床》 CAS 2012年第4期265-266,共2页 Cancer Research and Clinic
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