破壁提油灵芝孢子粉羧甲基化研究

Study on carboxy methyl modification of sporoderm-broken and defatted Ganoderma lucidum spores

以破壁提油灵芝孢子粉(SDGLS)为原料,以氢氧化钠为催化剂,氯乙酸为醚化剂,对破壁提油灵芝孢子粉的羧甲基化进行了研究。结果表明,制备羧甲基破壁提油灵芝孢子粉的较佳工艺条件为:SDGLS 1.00g,80%的乙醇20mL,氢氧化钠用量1.20g,氯乙酸用量1.18g,碱化时间2h,醚化温度45℃、醚化时间20h。此条件下,羧甲基破壁提油灵芝孢子粉的取代度(DS)达0.78,溶解率高达91%。

SDGLS （sporoderm-broken and defatted Ganoderma lucidum spores） was carboxy methylated with chloroactic acid in etherification reaction catalyzed by sodium hydroxide. The results indicated optimal conditions：SDGLS lg,80% ethanol 20mL,sodium hydroxide 1.20g,chloroactic acid 1.18g,alkalization time 2h, temperature 45~C, etherification time 20h. Under the conditions,the degree of substitution （DS） was 0.78, and dissolving rate was 91%.