5-硝基糠醛缩胺类化合物的合成

Synthesis of 5-nitro-furfuralimine compounds

以糠醇为原料,经酯化,硝化,水解,氧化制得关键中间体5-硝基糠醛,总收率51%;再与胺类化合物反应合成了一系列5-硝基糠醛缩胺类化合物,收率71%～89%.产物及中间体经IR,1H NMR,MS确证结构.

The key intermediate of 5 - nitro - furfuraldehyde was synthesized from furfuryl alcohol by esterifi- cation, nitration, hydration and oxidation, the total yield was 51%. A series of 5 - nitro - furfuralimine compounds were prepared form 5 - nitro - furfuraldehyde with various amines in the yield of 71% --89 %. The structures of the products and intermediate were confirmed by IR, 1H NMR and MS.