灯盏花素对氯化钡所致心律失常的预防作用

The Effects of Breviscapine On Experimental Arrhythmias Induced By barium Chloride

以静脉注射氯化钡 (8mg/kg)诱发大鼠发生多种心律失常 ,观察并比较灯盏花素、利多卡因、普萘洛尔对心律失常的预防作用。结果 :静脉注射灯盏花素 (8mg/kg)、利多卡因 (7.5mg/kg)及普萘洛尔 (1mg/kg)均可使大鼠心律失常发生时间推迟 ,严重程度减轻 ,死亡率降低 ,并缩短心律失常持续时间。灯盏花素的效果介于利多卡因与普萘洛尔之间。结果提示灯盏花素对氯化钡所致大鼠心律失常有较好的预防作用。

Comparing with Lidocaine and propernolol, We studied the effects of breviscapine on arrythmias induced by brarium chloride (Bacl 2). The result showed that brviscapine is superior to the control groups. It can delay the onset time. Shorten the duration. relieve the seriousness and reduce the death rate of arrythmias. Thus, the breviscapine might prevent the development of BaCl 2-induced arrythmia.