抗菌药物消耗及药敏结果统计分析

Analysis of Antibiotics Consumption

目的 :了解抗菌药物使用现状 ,为临床合理用药提供资料。方法 :统计住院病人对 14种抗菌药物药敏试验结果并与其他已知结果比较 ,用限定日剂量 (DefinedDailyDose ,DDD)计算抗菌药物的消耗 ,结合药敏结果和抗菌药消耗量的日DDD数 (DDDs/d)分析抗菌药物使用现状。结果 :院内菌对环丙沙星敏感率较其它已知结果高 ,对青霉素类、氨基糖苷类抗菌药敏感率低。环丙沙星、青霉素、庆大霉素、克林霉素的日消耗DDDs值分别居第 1～ 4位。结论 :环丙沙星、头孢菌素类、红霉素等药物的使用较为合理。氨基糖苷类、青霉素类、克林霉素使用存在不合理现象。

To get information on the current status of antibiotics consumption and to provide data for better use of these drugs, the results of drug sensitive tests in inpatients were statistically processed. The tests covered 14 antibiotics and the results were compared with the those obtained by other hospitals, the defined daily dose (DDD) was employed to evaluate the consumption of antibiotics. The results were combined with the those of drug sensitive tests and DDD per day to analyze the current status of use of antibiotics. It was found that susceptibility rate of bacteria in our hospital was higher than those of other hospitals and the rates to penicillin and gentamycin were lower than those in other hospitals. The top three antibiotics in terms of DDDs per day were, from high to low, ciprofloxacin, penicillin, gentamycin, and clindamyhcin. In our hospital, the use of ciprofloxacin, cephalosporins, erythromycin was reasonable but use of aminoglycosides and penicillins was, to some extent, not reasonable.