安今益的基础研究与临床功用

Base study and Clinical effect of Angeliq

绝经后妇女由于卵巢功能衰退,性激素水平的明显改变,可能发生躯体、精神、心理等方面的症状,出现潮热、失眠、易怒等更年期症状且患骨质疏松、心血管疾病等疾病的概率也会大大增加。因此地合理地激素补充治疗至关重要。安今益(Angeliq)含低剂量的天然雌激素及对控制血压和体重有利的孕激素-屈螺酮(Drospirenone,DRSP),可以使妇女在改善更年期症状的同时,降低心血管病的风险,有更多的受益。本文将对安今益的基础研究以及临床功用进行综述。

Postmenopausal women suffered from menopausal symptoms, come from the body, consciousness and psychology like hot flushes, insomnia and irascibility due to the level of hermones had changed obviously because of declining of overy funetion during menopause. Furthermore the probability of osteoporosis and cardiovascular disease had greatly increased. Thus hormone replacement therapy reasonably is more important. Angeliq, combination with low-dose nature estrogen and progestin-drospirenone ,that showed benefit to control blood pressure and weight, may improve the menopausal symptoms and reduce the risk of cardiovascular disease,that＇ s the potential additional benefit.