呼气挥发性有机物检测在癌症诊断中的应用

Exhaled volatile organic compounds detection in cancer diagnosis

挥发性有机化合物（VOC）是一类在常温下以蒸汽形式存在的有机物。人体内多种代谢及氧化应激反应可产生内源性VOC，它们通过血流最终到达肺部并排出体外。各种研究表明，人体处在癌症、炎症等病理状态下，呼气中VOC成分会产生显著变化。应用敏感度极高的仪器对其检测，不仅有可能在早期发现疾病，还能做到检查的无创和便捷，减少患者痛苦。因此，呼气VOC检测在肺癌等肿瘤性疾病的早期诊断中具有广阔的应用前景。

Volatile organic compounds （VOCs） are organic chemicals which can exist in the form of vapor at room temperature. Endogenous VOCs can be produced by different biochemical processes in the human body. They can be transfered to lung through bloodstream and released through breath. Many researches show that exhaled VOCs can be significantly changed when people suffering cancers or inflammation. Detecting exhaled VOCs through instrument with high sensitivity make it possible to detect cancers in early phase in a noninvasive and rapid way, which reduce the suffering of patients. In conclusion, exhaled VOCs detection is a promising method for early diagnosis of cancers.