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电生理检查在Brugada综合征危险分层中的价值 被引量：1

The Role of Electrophysiologic Testing in Risk Stratification in Patients with Brugada Syndrome
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摘要 Brugada综合征是一种遗传性心律失常疾病,约1/3的患者是由于心脏离子通道基因,主要是SCN5A基因的突变所致。患者可表现出各种心律失常,包括室上性心动过速、房室传导延缓或阻滞。
作者 石亮 刘兴鹏 杨新春
机构地区 首都医科大学附属北京朝阳医院心脏中心
出处 《心血管病学进展》 CAS 2012年第3期287-289,共3页 Advances in Cardiovascular Diseases
关键词 BRUGADA综合征 电生理检查 危险分层 遗传性心律失常 SCN5A基因 室上性心动过速 价值 离子通道基因
分类号 R541.7 [医药卫生—心血管疾病]
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参考文献11

  • 1Brugada J, Brugada R, Brugada P. Determinants of sudden death in individuals with the electrocardiographic pattern of Brugada syndrome and no previous cardi- ac arrest [ J ]. Circulation, 2003,108:3092-3096.
  • 2Brugada P, Brugada R, Mont L, et al. Natural history of Brugada syndrome: the prognostic value of programmed electrical stimulation of the heart [ J ]. J Car- diovasc Electrophysiol, 2003,14:455-457.
  • 3Giustetto C, Drago S, Demarchi PG, et al. Risk stratification of the patients with Brugada type electrocardiogram: a community-based prospective study[ J ]. Europace, 2009,11: 507-513.
  • 4Priori SG, Napolitano C, Gasparini M, et al. Natural history of Brugada syn- drome : insights for risk stratification and management [ J ]. Circulation, 2002, 105 : 1342-1347.
  • 5Probst V, Veltmann C, Eckardt L, et al. Long-term prognosis of patients diag- nosed with Brugada syndrome: results from the FINGER Brugada syndrome reg- istry[J]. Circulation, 2010,121:635-643.
  • 6Ohgo T, Okamura H, Noda T, et al. Acute and chronic management in patients with Brugada syndrome associated with electrical storm of ventricular fibrillation [J]. Heart Rhythm, 2007, 4:695-700.
  • 7Hermida JS, Denjoy I, Clerc J, et al. Hydroquinidine therapy in Brugada syn- drome[Jl. J Am Coil Cardiol, 2004, 43: 1853-1860.
  • 8Mok NS, Chan NY, Chiu AC. Successful use of quinidine in treatment of elec- trical storm in Brugada syndrome [ J ]. Pacing Clin Electrophysiol, 2004, 27: 821-823.
  • 9Brugada J, Brugada R, Brugada P. Electrophysiologic testing predicts events in Brugada syndrome patients [ J ]. Heart Rhythm, 2011, 8 : 1595-1597.
  • 10Wilde AAM, Viskin S. EP testing does not predict cardiac events in Brugada syndrome [ J]. Heart Rhythm, 2011,8 : 1598-1600.

同被引文献24

  • 1刘长乐,李广平.基因源性心脏病——Brugada综合征的研究现状[J].中华临床医师杂志（电子版）,2011,5(21):6394-6397. 被引量：5
  • 2杨兵,曹克将,单其俊,李库林,夏耘,涂静,袁斌斌,龚杰.1 065例健康汉族人Brugada心电图征发生率的初步调查[J].中华心律失常学杂志,2005,9(3):214-217. 被引量：24
  • 3Hilal T,Woods R.A tick-borne illness unmasking asymptomatic Brugada syndrome[J].Oxf Med Case Reports,2015,2015(2):191-193.
  • 4Badri M,Patel A,Yan GX.Cellular and ionic basis of J-wave syndromes[J].Trends Cardiovasc Med,2015,25(1):12-21.
  • 5Huang L,Liu C,Tang S,et al.Postmortem genetic screening of SNPs in Ry R2 gene in sudden unexplained nocturnal death syndrome in the southern Chinese Han population[J].Forensic Sci Int,2014,235:14-18.
  • 6Le Scouarnec S,Karakachoff M,Gourraud JB,et al.Testing the burden of rare variation in arrhythmia-susceptibility genes provides new insights into molecular diagnosis for Brugada syndrome[J].Hum Mol Genet,2015,24(10):2757-2763.
  • 7Hasegawa K,Ashihara T,Kimura H,et al.Long-term pharmacological therapy of Brugada syndrome:is J-wave attenuation a marker of drug efficacy[J]?Intern Med,2014,53(14):1523-1526.
  • 8Nielsen MW,Holst AG,Olesen SP,et al.The genetic component of Brugada syndrome[J].Front Physiol,2013,4:179.
  • 9Antzelevitch C,Yan GX.J wave syndromes[J].Heart Rhythm,2010,7(4):549-558.
  • 10Bayés de Luna A,Brugada J,Baranchuk A,et al.Current electrocardiographic criteria for diagnosis of Brugada pattern:a consensus report[J].J Electrocardiol,2012,45(5):433-442.

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心血管病学进展
2012年 第3期

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