肾脏交感神经射频消融术治疗顽固性高血压的研究现状与展望

Current Use of Renal Sympathetic Nerve Radiofrequency Ablation in Treatment of Resistant Hypertension

顽固性高血压是指临床上经过使用包括利尿剂在内的、足量且合理的3种或以上抗高血压药物治疗,血压仍未能控制在140/90 mm Hg以下目标值,对于患有糖尿病或肾脏疾病者未能降至130/80 mm Hg以下的高血压。顽固性高血压治疗棘手,预后差,为困扰当今医学界的一大难题。近年来有澳大利亚学者Krum等采用经皮导管肾脏交感神经射频消融术治疗顽固性高血压取得了初步成就,且实验正在向随机、多中心、大样本量标准深化,为顽固性高血压的治疗提供了一条新思路。现将对肾脏交感神经射频消融治疗在顽固性高血压治疗中的研究现状做一综述。

Resistant hypertension is defined as blood pressure that is above the target value of 140/90mm Hg,for people with diabetes or kidney disease failed to fall to below 130/80mm Hg.After treatment scheme three or more antihypertensive drug including diuretics adequately and reasonably,the treatment of resistent hypertension is intractable,poor prognosis,as a problem of current medical circles.In recent years the Australian scholar Krum using percutaneous catheter renal sympathetic nerve radiofrequency ablation for the treatment of resistent hypertension has achieved initial success,and the experiment is deepening to randomized,multicenter,large sample sizes standard,which provides a new train of thought for the treatment of resistant hypertension.This article will do a review on renal sympathetic nerve radiofrequency ablation in the treatment of resistant hypertension.