摘要
过去的十几年里,心脏再同步化治疗(CRT)被广泛地用于严重的心力衰竭患者。临床研究表明,CRT能明显改善重度心力衰竭患者症状和生活质量等,最新国际指南也将重度心力衰竭患者作为CRT治疗的I类适应证。但CRT在轻中度心力衰竭患者中的应用前景和疗效仍不是很清楚。现对CRT改善心功能的机制及其在轻度心力衰竭的临床应用和研究结果做一综述。
Cardiac resynchronization therapy（CRT） has been used as a treatment for patients with drug-refractory,chronic heart failure for many years.Clinical studies have shown a statistically significant improvement in symptoms and increased quality-of-life scores for patients being given CRT.Current guidelines consider CRT to be a class I indication for heart failure patients in NYHA functional classes Ⅲ to Ⅳ.However,the efficacy and application of CRT for patients with mildly symptomatic heart failure is not clear.This article reviews and discusses the results of trials using CRT mild heart failure in NYHA functional classⅠtoⅡ.
出处
《心血管病学进展》
CAS
2012年第3期421-423,共3页
Advances in Cardiovascular Diseases
关键词
心脏再同步化
轻中度心力衰竭
非同步化
cardiac resynchronization
mild heart failure
cardiac dyssynchrony
