基于激活强度分析的fMRI图像区域性特征研究

Characterization of the Regional fMRI Pattern Based on the Maximum Activation Intensity

基于ROI方法研究视皮层的兴奋模式,并提取志愿者的共同特征。结合生理结构与Talairach坐标系,对每位志愿者的三维皮层模型进行相同标准的ROI划分,将ROIs投射到保留拓扑关系的二维皮层模型,并提取每个ROI中比例最大的激活强度值来表征激活特征。提取志愿者各个ROI的共同激活特征,以此研究具有共同特征的视皮层兴奋模式。实验结果表明,该方法可提取志愿者的共同激活特征,克服了传统体素分析方法的局限性,为提取具有共同特征的视皮层兴奋模式建立了一种方法。

The activity pattern in human visual cortex is studied and the common feature of volunteers is extracted based on analysis of regions of interest（ROI）.By combining physiological structure and Talairach coordinates system,the same ROIs are obtained from the three-dimensional cortical model of each volunteer,these ROIs is then projected into the two-dimensional cortical model with the same topology,and the maximum activation intensity of each ROI is extracted.The common activation feature of volunteers is drawn and described via statistical analysis of ROIs.Experiment results show that the proposed method overcomes the limitation of traditional voxel-based analysis in extracting the common activation feature of volunteers.