原发性高血压患者代谢综合征发病情况与相关因素探讨

Analysis on the incidence of metabolic syndrome and relative factors in 112 patients with essential hypertension

目的探讨代谢综合征（MS）在原发性高血压患者中的发病情况及其相关因素。方法调查112例原发性高血压患者中代谢综合征发病情况，并根据有无代谢综合征发病分为两组，比较两组患者年龄、性别、腹围、体重指数、空腹血糖及血脂指标。结果112例高血压患者中符合代谢综合征诊断者共53例，检出率为47．32％。MS发病年龄主要集中于45-64岁，且女性腹型肥胖率及低HDL-C血症患者明显多于男性（P〈0．05），而男性FPG升高患者明显多于女性（P〈0．05）。MS组平均年龄、腹围、体重指数、肥胖率、血脂指标TG、TC、HDL-C及FPG均较非MS组差异有统计学意义（P〈0.05或P〈0．01）。结论原发性高血压患者MS发病率相对较高，MS发病主要与患者年龄、腹围、体重指数、空腹血糖及血脂有关。

Objective To explore the incidence of metabolic syndrome （MS） and relative factors in patients with essential hypertension. Methods The incidence of MS was investigated in 112 patients with essential hyperten- sion. The patients were divided into MS group and non-MS group based on whether they were complicated with MS. The age, gender, waist circumference （WC）, body mass index （BMI）, fasting plasma glucose （FPG） and lipid parame- ters were compared between the two groups. Results The incidence of MS in 112 patients with essential hyperten- sion was 47.32% （53/112）, mainly concentrating on patients of 45-64 years old. And the incidence of abdominal obesi- ty and the percentage of low high density lipoprotein cholesterol （HDL-C） was significantly higher in females than males （P〈0.05）, while the number of high FPG was significantly higher in males than in females （P〈0.05）. There were significantly difference between the MS group and non-MS group in age, WC, BMI, obesity rates, triglycerides （TG）, the total cholesterol （TC）, HDL-C and FPG. Conclusion Relative higher incidence of MS can be found in patients with essential hypertension, which is correlated with age, WC, BMI, FPG and blood lipids.