围手术期患者低蛋白血症与胃瘫的相关性研究

Correlative study of hypoproteinemia and postsurgical gastroparesis syndrome during the perioperative period

目的探讨围手术期患者低蛋白血症与术后胃瘫的关系。方法随机选取200例腹部手术患者,比较术后胃瘫患者与无胃瘫患者的围手术期平均蛋白水平,分析胃瘫治疗期平均蛋白水平与胃瘫治疗时间的关系。结果 200例患者共14例出现胃瘫,胃瘫患者围手术期平均蛋白水平为(26±3.1)g/L,186例患者围手术期平均血清白蛋白水平为(31±6.5)g/L。胃瘫患者围手术期平均蛋白水平低于无胃瘫患者(P<0.05)。14例胃瘫患者中,胃瘫治疗期间平均蛋白水平越高,胃瘫治疗期越短,两者呈负相关关系(r=-0.42,P<0.05)。结论低蛋白血症是发生PGS的危险因素,提高蛋白水平是治疗胃瘫一个关键环节。

Objective To investigate the relationship between hypoproteinemi with postsurgical gastropare- sis syndrome （PGS） during the perioperative period. Methods Two hundred patients accepted abdominal operations were randomly selected. The levels of albumin during the perioperative period were compared between the PGS pa- tients and the Non-PGS patients. The relationship of the treatment period of PGS and the average levels of albumin were analyzed. Results Of the 200 patients, 14 were found with PGS, of which the average albumin levels during the perioperative period was （26±3.1） g/L, lower than those of the remaining 186 patients [（31±6.5） g/L], P〈0.05. The treatment period of PGS was shorter when the average albumin level was higher, showing a negative correlation （ r=-0.42, P〈0.05）. Conclusion Hypoproteinemia is a risk factor of PGS. Raising the albumin level is a key point in the treatment of PGS.