肺癌患者医院感染调查分析

Analysis of nosocomial infection in lung cancer patients

目的对肺癌患者发生医院感染的状况进行调查分析。方法对126例肺癌患者发生医院感染的状况进行分析。结果 126例肺癌患者中分离出病原菌148株,病原菌以革兰氏阴性杆菌为主(62.84%),革兰氏阳性杆菌(29.73%),真菌(7.43%);细菌的耐药性普遍较高;感染的相关因素有:年龄、住院时间、肺癌临床分期、侵袭性操作、放疗/化疗、抗生素的使用、免疫抑制剂或激素、伴有基础疾病。结论肺癌患者医院感染病原菌以革兰氏阴性杆菌为主,病原菌常为多药耐药。合理控制院内感染的相关因素,对指导临床合理用药具有重要意义。

Objective To explore the situation of nosocomial infection in lung cancer patients in order to provide a basis for the clinical use of drugs.Methods The nosocomial infection in 126 cases o f lung cancer patients were retrospectively analyzed.Results A total of 148 pathogen strains were isolated from 126 cases.The main pathogenic bacteria were the Gram-negative bacilli pathogens（62.84%）,Gram-positive bacteria（29.73%）,and fungi（7.43%）;Bacterial drug resistance was generally high;Statistically analysis confirmed that the nosocomial infection rate was obviously related with age,length of stay,lung cancer,clinical stage,invasive operation,radiotherapy/chemotherapy,the use of antibiotics,immunosuppressive agents or hormones,associated with underlying diseases.Conclusion The main pathogenic bacteria of nosocomial infection in lung cancer patients are the Gram-negative bacilli pathogens,which are often multi-drug resistant pathogens.Reasonable control the nosocomial infections related factors has important roles in guide the clinical drugs use.