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53例家族性乳腺癌BRCA1和BRCA2基因部分序列的突变分析 被引量:5

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摘要 BRCA1和BRCA2是家族性乳腺癌(familialbreastcancer,FBC)的主要易感基因,均为抑癌基因。BRCA1的异常与45%的家族性乳腺癌、卵巢癌有关;BRCA2的异常不仅与45%的家族性乳腺癌有关,尚与早发乳癌、男性乳癌关系密切。这两个基因在人群...
出处 《北京医科大学学报》 CSCD 2000年第1期86-86,共1页 Journal of Peking University(Health Sciences)
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