啜粥、温覆对桂枝汤药效的影响

Pharmacological Effect of the Decoction of Cinnamon Twigs CombinatiOn with Taking Gruel and Warming

以桂枝汤口饲动物,17.5和35g/kg·d剂量组对小鼠流感病毒性肺炎有抑制作用,对病鼠的单核巨噬细胞系统吞噬活性有增强作用。给相同剂量桂枝汤后45min,再给予热粥,并提高环境温度,从22℃升高到27℃,维持1h,与单纯给药组相比,能显著提高对小鼠流感病毒性肺炎的抑制作用,也有增强病鼠单核巨噬细胞系统吞噬活性的倾向。上述结果对《伤寒论》所述桂枝汤服后啜粥、温覆以助药力的认识,提供了一定的实验说明。

The inhibitory action on the pneumonia caused by influenza virus in mice with the dose of 17.5-35g crude drug/kg/day p.o. of the Decoction of Cinnamon Twigs(DCT)was found. The administration of DCT also enhanced the phagocytosis of the reticuloendothelial system in mice with pneumonia. Taking gruel and raising the environmental temperature from 22℃ to 27℃ for 1 hour in 45 minutes after administration, the inhibitory, action was incerased-significantly,and a tendency to enhance the phagoeytosis was appeared. The experimental result gave support to that the taking gruel and warming after administration could contribute to medicinal effectiveness of DCT as diseribed in 'Treatise on Febrile Diseases'.