期刊文献+

奥硝唑栓治疗复发性细菌性阴道病200例疗效分析 被引量:3

Ornidazole Suppository in the Treatment of Recurrent Bacterial Vaginosis : Clinical Analysis of 200 Cases
下载PDF
导出
摘要 目的探讨奥硝唑栓联合乳酸菌素阴道胶囊治疗复发性细菌性阴道病的临床疗效。方法将200例复发性细菌性阴道炎的患者随机分为两组,对照组用奥硝唑栓治疗1周100例,治疗组100例用奥硝唑栓治疗1周,同时治疗组在随后月经期前分别用乳酸菌素阴道胶囊7d连续2个疗程100例;用药后观察治疗后两组的有效率及复发率。结果两组患者停药后1个月,2个月,3个月,6个月治疗组有效率明显高于对照组(P<0.05),治疗组复发率明显低于对照组(P<0.05)。结论奥硝唑栓联合乳酸菌素阴道胶囊在随后月经期前用药有效的减少细菌性阴道病的复发,其远期效果良好。 Objective To investigate the clinical curative effect of ornidazole suppository combined with lactobacillus vaginal capsules in the treatment of recurrent bacterial vaginal disease. Methods 200 cases of recurrent bacterial vaginosis patients were randomly divided into two groups each with 100 cases. Both of two groups were used with ornidazole suppository and continuous medication one weeks. Before the subsequent menstrual, the treatment group received lactobacillus vaginal capsules used for 7 days, and continued treatment for 2 courses. Then efficiency and recurrence rate of two groups were observed. Results Observing two groups of effective treatment and the recurrence rate after treatment 2 months, 3 months, 6 months and 12 months, the effective rate of treatment group was significantly higher than that of the control group ( P 〈 0.05), the recurrence rate of treatment group was significantly lower than the control group ( P 〈 0.05). Conclusion Ornidazole suppository combined with lactobaciUus vaginal capsules reduce bacterial vaginal disease recurrence, the long-term effect is good.
作者 黄静
出处 《国外医药(抗生素分册)》 CAS 2012年第3期138-141,共4页 World Notes on Antibiotics
关键词 奥硝唑栓 乳酸菌素阴道胶囊 复发性细菌性阴道病 月经期前用药 远期疗效 ornidazole suppository lactobacillus vaginal capsules recurrent bacterial vaginosis menstrual period before medication long term efficacy
  • 相关文献

参考文献2

二级参考文献25

  • 1刘雪梅,马琳.唯阴康联合定菌生治疗妊娠期细菌性阴道病的临床观察[J].职业与健康,2007,23(20):1896-1897. 被引量:3
  • 2Gregor Reid, Andrew W. Bruce.Could probiotics be an option for treating and preventing urogenital infections? Medscape General Medicine(TM),2001,21(9):351-358.
  • 3Van Kessel, Katherine MD,Assefi, et al. Common complementary and alternative therapies for yeast vaginitis and bacterial vaginosis: a systematic review.Obstetrical &amp; Gynecological Survey,2003,58(5):351-358.
  • 4Wilks M,Thin RN,Tabaqchali S. Quantitative methods for studies on vaginal flora.J Med Microbiol ,1982,15(79):141-147.
  • 5Nord CE.Ecological treatment of bacterial vaginosis.Lancetl,1987,287.
  • 6Andersch B, Forssman L, Lincoln K, et al. Treatment of bacterial vaginosis with an acid cream: a comparison between the effect of lactate-gel and metronidazole.Gynecol Obstets Invest,1986,21(1):19-25.
  • 7Hallen A.Treatment of bacterial vaginosis with lactobacilli.Sex Transm Dis,1992,19(13):146-148.
  • 8Chimura T, Funayama T, Murayama K, et al.Ecological treatment of bacterial vaginosis.Jpn J Antibiot, 1995,48(3):432-436.
  • 9Parent D.Therapy of bacterial vaginosis using exogenously-applied lactobacilli acidophili and a low dose of estoiol:a placebo-controlled multicentric clinical trall.Arzneimittelforschung,1996,46(1):68-73.
  • 10Andreeva P, Dimitrov A. The proiotic Lactobacillus acidophilus-an alterative treatment of bacterial vaginosis. Akush Ginekol (Soffia), 2002,41(6): 29-31.

共引文献64

同被引文献35

  • 1杨晓,黎行山,梁小余.滴虫性阴道炎3种硝基咪唑类药物治疗方案的成本-效果分析[J].中国药房,2005,16(22):1716-1718. 被引量:14
  • 2曲彩红,谌小卫,黄敏,陶玲,麦海燕.4种给药方案治疗滴虫性阴道炎的成本-效果对比研究[J].中国医院用药评价与分析,2005,5(6):371-373. 被引量:12
  • 3王也玲,蔡玉群,麻亚茜,吕雯.奥硝唑胶囊治疗滴虫性阴道炎30例疗效分析[J].中国医师杂志,2006,8(11):1575-1576. 被引量:12
  • 4张玉新,任细妹.维生素C治疗细菌性阴道病疗效观察[J].中国妇幼保健,2007,22(4):450-452. 被引量:7
  • 5郑修霞,安力彬,顾平.妇产科护理学.北京:人民卫生出版社,2011,184-185.
  • 6ALFONSI G A, SHLAY J C, PARKER S, et al. Clinical inquiries. What is the best approach for managing recurrent bacterial vaginosis? [J]. J Fam Pract,2004,53 (8) :650- 652.
  • 7BRADSHAW C S,MORTON A N, HOCKING J,et al. High recurrence rates of bacterial vaginosis over the course of 12 months after oral metronidazole therapy and factors associated with recurrence [ J ]. J Infect Dis, 2006, 193 (11) :1478-1486.
  • 8SOBEL J D, FEORRIS D,SCHWEBKE J, et al. Suppressive antibacterial therapy with 0.75% metronidazole vaginal gel to prevent recurrent bacterial vaginosis [ J ]. Am J Obstet Gyneco1,2006,194 (5) : 1283-1289.
  • 9LARSSON P G, STRAY-PEDERSEN B, RYTTIG K R, et al. Human lactobacilli as supplementation of clindamycin to patients with bacterial vaginosis reduce the recurrence rate ; a 6-month, double-blind, randomized, placebo-controlled study[J]. BMC Womens Health,2008,8( 1 ):3.
  • 10DECENA D C, CO J T, MANALASTAS R M, et al. Metronidazole with lactacyd vaginal gel in bacterial vaginosis [ J ]. J Obstet Gynaecol Res, 2006,32 ( 3 ) : 243 - 251.

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部