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CYP2C19遗传多态性与药物代谢及疗效的研究进展 被引量:13

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摘要 CYP2C19是一种重要的药物代谢酶,参与多种药物的体内代谢。该酶的活性在不同个体和种族之间存在着显著的差异。本文综述了CYP2C19酶的遗传多态性对药物代谢及疗效的影响,将为临床确定最佳治疗剂量、制定合理用药方案、发挥最大疗效、避免和减少不良反应提供指导依据。
出处 《当代医学》 2012年第16期21-23,共3页 Contemporary Medicine
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