早发型重度子痫前期期待治疗对母婴结局影响的探讨

Study about Maternal and Neonatal Outcomes of Expectant Treatment in Early Onset of Severe Preeclampsia

目的:探讨早发型重度子痫前期期待治疗对母婴结局影响。方法:回顾性分析我院2009年12月至2010年6月收治的140例早发型重度子痫前期患者的临床资料,按照孕周的不同分为A组(<28周)、B组(28～31+6周)和C组(32～34周),比较三组患者的母婴结局。结果:随着孕龄的延长,并发症的发生率逐渐降低,但A、B、C三组无显著性差异(P>0.05);B组的治疗时间显著长于A、B两组(P<0.05);A组以引产为主,B、C组以剖宫产为主,A组与B、C组有显著性差异(P<0.05);随着孕龄的延长,胎死宫内、新生儿窒息、死亡率的逐渐降低,A组与B、C组有显著性差异(P<0.05)。结论:早发型子痫前期患者的孕周越小,母婴的预后越差,短期的保守治疗可有效的延长孕周,同时在适当的时候采取合适的方式终止妊娠,可改善母婴结局。

Objective：To investigate expectant treatment effects of early onset of severe preeclampsia on maternal and neonatal outcomes.Methods：140 cases of early onset severe preeclampsia patients were retrospective analyzed in our hospital from 2009 Dec to 2010 Jun,according to the different gestational weeks were divided into group A（〈28 weeks）,group B（28 ~31＋6 week） and group C（32 to 34 weeks）,were compared the maternal and neonatal outcomes between the three groups.Results：With the gestational age of the extension,the complication rate was reduced gradually,but A,B,C three groups had no significant difference（P〉0.05）;The treatment time was longer than that in group B A,B two group（P〈0.05）;group A to induction of labor,B,group C with cesarean section production mainly,A group and B group,C had significant difference（P〈0.05）;with the gestational age of the extension,intrauterine fetal death,neonatal asphyxia,mortality decreased gradually,and the B A group,C group were significantly different（P〈0.05）.Conclusion：Early onset preeclampsia pregnant is less,maternal-fetal prognosis is worse,short-term conservative treatment can effectively prolong gestational weeks,at the same time can take appropriate way to terminate the pregnancy at the appropriate time,may improve pregnancy outcome.