p53在皮肤常见良恶性疾病中的研究进展
摘要
p53基因有野生型和突变型两种。野生型有抑制某些促进细胞有丝分裂酶活性的作用,阻碍细胞进入DNA合成期,抑制了细胞的分裂和增殖,使被损伤的DNA有时间得以修复;或者启动程序性死亡过程,防止细胞的恶变。突变型的p53基因失去对细胞生长的抑制作用。
出处
《中国医药导刊》
2012年第5期858-859,847,共3页
Chinese Journal of Medicinal Guide
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