介入治疗应用于老年恶性梗阻性黄疸患者的临床疗效观察

Interventional Treatment for Application in Elderly Patients with Malignant Obstructive Jaundice the Clinical Curative Effect of Observation

目的:探讨介入治疗在老年患者恶性梗阻性黄疸治疗过程中的临床效果、费用与安全性。方法:选择笔者所在医院2005年1月-2010年12月住院治疗的恶性梗阻性黄疸老年患者126例,将患者根据治疗方法分为观察组与对照组,观察组进行经皮经肝穿刺胆管引流术介入治疗,对照组进行开腹手术引流治疗,对比两组患者的疗效、并发症与治疗费用。结果:两组患者治疗后的血清胆红素含量与治疗前相比均显著降低(P<0.05),组间相比无统计学意义(P>0.05),血清胆红素下降超过50%的时间组间比较无统计学意义(P>0.05),观察组并发症发生率与对照组相比显著降低(P<0.05),与对照组相比平均住院时间、平均住院费用显著减少(P<0.05)。结论:介入治疗老年恶性梗阻性黄疸能够取得与开腹引流同样的显著疗效,还能够减少并发症,降低治疗时间与费用,应当掌握好治疗指征广泛推广。

Objective ：To discusses intervention in older patients with malignant obstructive jaundice clinical effect in the course of treatment, cost and safety.Methods ：From January 2005 to December 2010 in author＇ s hospital hospitalization nausea block sex was icteric elderly patients, patients were divided into two groups according to the treatment method, the observation group undergone percutaneous puncture of the liver bile duct drainage interventional therapy, the Control group was given open operation control drainage treatment, compared to two groups of patients, and the effect of complications treatment costs.Results ：Two groups of patients after treatment of serum bilirubin content and were significantly lower than before treatment （P〈0.05）, compared the two groups no significant difference （P〉O.05）, serum bilirubin fell more than 50% of the time had no significant difference （P〉0.05）, the observation group complication rate compared with the control significantly reduced（P〈O.05）, the average length of hospital stay, average hospitalization cost significantly reduced（P〈O.OS）.Conclusion ：Older malignant obstructive jaundice intervention can be achieved and open drainage of the same remarkable curative effect, still can reduce the complications and reduce time to treatment and cost, should grasp the treatment indications widely.