异舒吉治疗冠心病合并急性左心衰的临床研究

Clinical research of Isosorbide Dinitrate Spray in treating CHD with acute left ventricular failure

目的探讨异舒吉治疗冠心病合并急性左心衰的疗效。方法 123例异舒吉治疗冠心病合并急性左心衰患者,分为治疗组62例,对照组61例,并常规治疗。治疗组用异舒吉30mg微泵入,对照组使用硝酸甘油30mg微泵入,根据胸痛、血压等变化调整速度。观察两组在症状和体征的改变。结果观察组临床总有效率为93.55%,明显高于对照组83.61%,P<0.05,差异有统计学意义。结论异舒吉救治冠心病合并急性左心衰疗效显著。

Objective To investigate the efficacy of Isosorbide Dinitrate Spray in treating CHD with acute left ventricular failure. Methods 123 cases of CHD patients with acute left ventricular failure were divided into the treatment group ,62 cases, and the control group, 61 cases. Both groups received conventional treatment. The patients in the treatment group got 30 mg of Isosorbide Dinitrate Spray micro- pumped into 30 mg of nitroglycerin was micro-pumped into the patients in control group, and the speed was adjusted according to chest pain and blood pressure changes. Observed the signs and symptoms of change in two groups. Results The total effective rate of the treatment group was 93.55 %, significantly higher than 83.61% of the control group （P 〈0.05）, the difference was statistically significant. Conclusions Isosorbide Dinitrate Spray has significant efficacy in treating CHD with acute left ven- tricular failure.