绍兴母乳中有机氯农药蓄积水平及趋势分析

Accumulative level and trend analysis of organochlorine pesticides in the breast milk in Shaoxing

目的:了解绍兴市正常居民母乳中有机氯的蓄积水平及动态变化趋势。方法:母乳经冷冻干燥后,加入同位素内标,经乙腈萃取,凝胶色谱净化,用气相色谱-质谱联用仪测定母乳中有机氯残留。结果:母乳中HCB中位值在检出限以下,总BHC、总DDT的中位值分别为698.7 ng/g脂肪和50.8 ng/g脂肪。母乳中BHC含量随着年龄增大而增高。1983-2009年绍兴市母乳中总BHC、总DDT分别下降99.8%和99.7%,1988年-2009年HCB下降90.0%。结论:绍兴市母乳中有机氯蓄积水平已处于相对安全水平。

Objective：To evaluate accumulative level and dynamics trend of organochlorine pesticides in the breast milk in Shaoxing.Methods： Breast milk was added 13C labeled internal standard after freeze-drying.Then the sample was extracted by acetonitrile,purified by gel permeation chromatography（GPC）,and analyzed by gas chromatography coupled to mass Spectrometry under SIM mode.Results： The median of HCB was below the detection limit level.The geometrical mean levels of BHC and DDT residues were 698.7 ng/g lipid and 50.8 ng/g lipid respectively.BHC residue increased progressively together with advancing age.BHC and DDT residues decreased by 99.8% and 99.7% separately from 1983 to 2009.HCB residue reduced 90.0% from 1988 to 2009.Conclusion： The study showed that the breast milk in Shaoxing was relatively safe.