2009年-2010年宁波市甲型流感的流行与人群抗体水平变化

Influenza A prevalence and antibody level changes in population of Ningbo from 2009 to 2010

目的:了解2009年-2010年宁波市甲型流感病毒的流行特征人群抗体水平的变化情况。方法:流感监测哨点医院采集标本进行流感病毒分离及疫情监测,在流感流行高峰初期及流行高峰结束后于各县区采集双份血清进行流感抗体检测。结果:2009年甲型流感极其活跃,尤其在2009年9月份,季节性甲1、甲3亚型和新甲型H1N1同时出现流行。对分别于2009年7月与2010年3月份所采人群血清的抗体检测结果,季节性甲1、甲3及新甲型H1N1亚型的抗体阳性率分别为16.26%～26.88%、63.34～73.66%和6.99%～29.21%。结论:2009年3种甲型流感病毒的亚型在同一时间内混合流行。人群双份血清流感抗体测定结果提示,新甲型H1N1流感的流行强度要明显高于季节性甲型流感。

Objective：To understand the epidemic characteristics of influenza A virus and antibody levels changes in population from 2009 to 2010 in Ningbo city.Methods： Specimens were collected from influenza surveillance sentinel hospitals for virus isolation and epidemic monitoring.In the early peak of the pandemic influenza and after the end of epidemic peak,double serum were collected in each county for detection of influenza antibodies.Results： Influenza was extremely active in 2009.In particular,in September 2009,the seasonal A 1,A 3 and the new influenza A H1N1 subtype were prevalent simultaneously.The test results of antibody from sera collected in July 2009 and March 2010 showed the antibody-positive rates of the seasonal A 1,A 3 and the new influenza A H1N1 subtype were 16.26%~26.88%,63.34%~73.66% and 6.99%~29.21%.Conclusion： In March of 2009,three subtypes of influenza virus were prevalent at the same time.Population double serum influenza antibody test results suggested that the new H1N1 influenza epidemic intensity was significantly higher than seasonal influenza.