血清胆汁酸在黄疸鉴别诊断和治疗中的价值

The value of serums bile acids in the differential diagnosis and treatment of jaundice

目的 :研究血清胆汁酸谱在黄疸鉴别诊断和治疗中的价值。方法 :采用高效液相色谱 (HPL C)反相聚合酶柱分离测定血清中 15种胆汁酸的含量 ,共 48例。结果 :健康人血清总胆汁酸 (s TBA)为 4.2 8±1.10 umol/ L ,黄疸病人的 s TBA明显升高 ,且 s TBA的组成因原发病的不同而各异。结论 :测定血清胆汁酸有助于黄疸的鉴别诊断 。

Objective: To investigate the value of serum bile acids in the differential diagnosis of jaundice.Methods:With unmobile phase enzymatic HPLC,48 persons'15 serum bile acids were quantitated.Results:The serum total bile acids (sTBA) of health adults was 4.28±1.10 umol/L,whereas that of the patients with jaundice was significantly elevated and the contents Varied with the causes of jaundice.Conclusion:In patients with hepatic billary-pancreatic diseases,there are various degrees obstacle in the metatolism of bile acids and specially in serum bile acid spectrum.The special serum bile acid spectrum plays a main role in the differential diagnosis of jaundice. [FK(WB00001。5]