莫西沙星注射液治疗重症社区获得性肺炎疗效观察

Effect of moxifloxacin on severe community acquired pneumonia

目的观察莫西沙星注射液治疗重症社区获得性肺炎的临床疗效。方法将符合入选条件的60例重症社区获得性肺炎患者分为治疗组和对照组,每组30例,两组基础治疗相似,治疗组患者予莫西沙星注射液250ml,静脉点滴,每天1次,共6d;对照组30例,予注射用头孢曲松钠2.0g加入0.9%氯化钠注射液250 mL,静脉点滴,每天1次,共6d。6d后,根据病情决定是否继续进行抗生素治疗。分别给予治疗前后临床疗效比较,同时检测治疗前、后的血常规及痰培养等。结果治疗组疗效(80%)明显优于对照组(60%),差异有统计学意义(P<0.05),且无不良反应。结论莫西沙星注射液治疗重症社区获得性肺炎疗效确切,安全可靠。

Objective To observe the curative effect of moxifloxacin injection on severe community acquired pneumonia.Methods Sixty cases with severe community acquired pneumonia were selected based on the diagnositic criteria and radomly divided into treatment group and control group each consisted of 30 cases.Patients in the treatment group were given moxifloxacin injection 250ml by IV drip,1/day,for 6 days;Those in the control group received ceftriaxone sodium for injection 2g in250mL0.9% sodium chloride injection vy IV drip,1/day,for 6 days.Then routine blood examination and sputum culture were conduceted and the clinical efficacy in both groups were compared before and after treatment.Results The effictive rate in the treatment group was 80% higher than that of the control group（60%）,showing significant difference（P0.05）without adverse reaction.Conclusion The curative effect of moxifloxacin injection in the treatment of severe community acquired pneumonia is accurate,safe and reliable.