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雌激素在阿尔茨海默病中的神经保护作用 被引量：3

Neuroprotective effects of estrogen in Alzheimer's disease
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摘要 阿尔茨海默病(Alzheimer's disease,AD)是一种进行性发展的神经退行性疾病。流行病学显示老年女性更容易患病,这可能与绝经后雌激素水平陡然下降有关。近年来研究发现雌激素的神经保护作用可能与降低AD发生的危险系数有关。本文对雌激素与AD相关的神经保护机制进行综述。 Alzheimer＇s disease （AD） is a progressive neurodegenerative disease. Epidemiological evidence shows ofter women are more susceptible to AD, which may be related with post - menopausal precipitous depletion of estrogens. Recent researches suggest that the neuroprotective effects of estrogen may be relevant to decrease the risk of AD. This review will make a brief summary on AD - related neuroprotective mechanism of estrogen.
作者 杨涛 姜妙娜 贾玉红
机构地区 大连医科大学病理生理学教研室
出处 《大连医科大学学报》 CAS 2012年第3期308-310,共3页 Journal of Dalian Medical University
关键词 雌激素 阿尔茨海默症 神经保护作用 Β淀粉样蛋白 estrogen Alzheimer＇s disease neuroprotection β- amyloid
分类号 R749.16 [医药卫生—神经病学与精神病学]
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参考文献23

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同被引文献63

  • 1姜晓蕊,卢宏,冯建玉,滕军放,宋志宇,王建平.17-β雌二醇对血管性痴呆大鼠BDNF表达的影响[J].实用神经疾病杂志,2005,8(2):39-41. 被引量：15
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引证文献3

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大连医科大学学报
2012年 第3期

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