超声造影在移植肾排斥反应中的诊断价值

The diagnostic value of contrast-enhanced ultrasound in renal allograft rejection

目的观测移植肾排斥反应的超声造影特点,分析造影图像,寻求超声造影诊断移植肾排斥反应的定量指标。方法选取患者30例,将患者分为A、B两组,A组20例肾功能异常和B组10例移植肾功能正常患者分别进行常规超声检查和超声造影检查,观察造影时微循环灌注情况并应用造影分析软件对感兴趣区域分析定量指标曲线下面积AUC(Area Under The Curve),然后进行统计分析。结果 A组移植肾微循环的灌注明显比B组差;A组与B组的分析指标AUC差异有统计学意义(P<0.05)。结论超声造影可以动态检测移植肾发生排斥反应时微循环灌注的改变;定量指标AUC为诊断移植肾排斥反应提供了较为可靠、客观的影像学依据。

Objective To observe characteristics of the renal allograft rejection in contrast-enhanced ultrasound and to analyse ultrasonic imaging and seek for the quantitative index of the diagnosis of the renal allograft rejection.Methods There were 20 cases of renal transplant patients with abnormality in group A and 10 cases in group B with normality,A and B were conducted normal routine ultrasound examination and contrast-enhanced ultrasound examination.The imaging of microcirculation was swreyed,and then perfusion application was analyed uwing software to the interested region to analyse quantitative index AUC（Area Under The Curve）,and statistical analysis was performed.Results Graft microcirculation infusion in group B was obviously better than that in group A;Analytical indicator（AUC） of group A and group B was statistically significant differences（P0.05）.Conclusion Contrast-enhanced ultrasound imaging can detect dynamically the changes of the graft microcirculation perfusion;Quantitative index（AUC） for diagnosis of renal allograft rejection provides a more reliable and objective imaging basis.