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帕金森病患者便秘发生的影响因素 被引量:3

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摘要 目的观察帕金森病(PD)患者便秘的发生率,探讨便秘发生的相关因素。方法采用卡方检验统计不同性别及不同治疗组患者便秘的发生率。采用逐步回归分析检验便秘的相关因素。结果 104例患者中,70例患者存在便秘,发生率为67.31%,不同性别及不同治疗组患者间便秘的发生率差异无统计学意义。而症状波动可作为PD患者便秘发生的一个危险因素。结论不同治疗药物与患者便秘的发生率无关,而症状波动加重便秘的发生。
出处 《江苏医药》 CAS CSCD 北大核心 2012年第10期1220-1221,共2页 Jiangsu Medical Journal
关键词 帕金森病 便秘
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  • 1Gibb WR, Lee AJ. The relevance of the lewy body to the pathogenesis of idiopathic Parkinson's disease[J]. J Neurol- Neurosurg Psychiatry, 1988,51 (6) : 745-752.
  • 2Abbott RD, Petrovitch H, White LR, et al. Frequency of bowel movements and the future risk of Parkinson's disease[J] Neurology, 2001,57(3) : 456-462.
  • 3Blandini F, Ralestra B, Levandis G, et al. Functional and neurochemieal changes of the gastrointestinal tract in a rodent model of Parkinson's disease [J]. Neuroscience Letters, 2009,467 (3) : 203-207.
  • 4Greene JG, Noorian AR, Srinivasan S. Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease [J]. Experimental Neuroiogy, 2009,218 (1) : 154-161.
  • 5Winge K,Rasmussen D,Werdelin LM. Constipation in neuro- logical diseases[J]. J Neurol Neurosurg Psychiatry, 2003,74 (1):13.
  • 6Singer C, Weiner WJ, Sanchez-Ramos JR. Autonomic dysfunction in men with Parkinsonrs disease [J ]. Eur Neurol, 1992,32(3) : 134-140.
  • 7Tuteja AK, Talley NJ, Joos SK, et al. Is constipation associated with decreased physical activity in normally active subjects[J]? Am J Gastroenterol, 2005,100(1) : 124-129.
  • 8Honig H, Antonini A, Martinez-Martin P, et al. Intrajejunal levodopa infusion in Parkinson's disease: a pilot multicenter study of effects on non-motor symptoms and quality of life [J]. Mov Disord, 2009,24(10) : 1468-1474.
  • 9Chiu CM, Wang CP, Sung WH, et al. Functional magnetic stimulation in constipation associated with Parkinson's dis- ease[J]. J Rehabil Med,2009,41(13) : 1085-1089.
  • 10Liu Z, Sakakibara R, Odaka T, et al. Mosapride citrate, a novel 5-HT4 agonist and partial 5-HT3 antagonist, ameliorates constipation in parkinsonian patients[J]. Mov Disord, 2005, 20(6) : 680-686.

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