鼻咽癌患者生存质量QOL-RTI／H＆N测评信度效度考核

Assessment of reliability and validity of QOL-RTI/H&N scale among nasopharyngeal carcinoma patients

目的:对QOL-RTI/H&N量表进行信度效度考核,以考评量表是否适合于鼻咽癌患者生存质量的测评。方法:收集中山大学肿瘤医院416例鼻咽癌患者的QOL-RTI/H&N和人口学资料,采用Cronbach’sα、相关分析、信度分析、证实性因子分析和方差分析考核量表的信度(α信度、分半信度和重测信度)、效度(结构效度)和区分度。结果:所有方面的Cronbach’sα系数和分半系数均>0.6,所有方面的重测系数均>0.7。总体模型的证实性因子分析显示,正规拟合指数、非正规拟合指数以及比较拟合指数都等于1,近似误差均方根RMSEA为0.000,95%RMSEA为(0.000;0.078)。不同放疗阶段的患者在所有方面的得分差异均有统计学意义(P<0.05),正在接受放疗患者的生存质量普遍较低。结论:QOL-RTI/H&N量表具有良好的信度、效度和区分度,可操作性强,可用于鼻咽癌患者的生存质量评价。

OBJECTIVE：To assess the reliability and validity of QOL-RTI/H＆N scale,and measure whether the scale is suitable to measure the QOL of nasopharyngeal carcinoma （NPC） patients. METHODS： the data of 416 NPC patients from Cancer Hospital of Sun Yat-sen University were collected. Split-half reliability, Cronbach＇ s a coefficient, construct validity, discriminant validity and feasibility of QOL-RTI/H＆N were analyzed. RESULTS： Cronbach＇s α coefficient and split-half reliability of all domains were greater than 0.6. Test-retest coefficient of all domains were greater than 0.7. The result of confirmatory factor a nalysis of all items showed that normed fit index,non-normed fit index,and comparative fit index were equal to 1. RMSEA were equal to 0. 000,and 95 % RMSEA was between 0. 000 and 0. 078. All the domain score and dimension scores of patients in different radiotherapy stage were significantly different （P〈0. 05）. The QOL of the NPC patients who were receiving RT were lower than other people. CONCLUSIONS： QOL-RTI/H＆N scale is a reliable and valid disease-specific instrument, with good respec tiveness. It can be used for evaluation QOL of NPC patients.