超声引导微波消融治疗肝脏转移性神经内分泌肿瘤

Ultrasound guided microwave ablation in treatment of liver metastases of neuroendocrine tumors

目的评估微波消融治疗肝脏转移性神经内分泌肿瘤的可行性、安全性及有效性。方法对6例(14个病灶)神经内分泌肿瘤肝脏转移患者行超声引导下微波消融治疗,观察肿瘤的大小变化、不良反应及并发症。结果技术有效率为92.86%(13/14)。术后1例患者出现发热,1例出现疼痛,1例病灶靠近膈肌者出现反应性胸腔积液,因疼痛诱发急性冠状动脉综合征。1例患者的1个病灶于治疗后3个月出现局部进展;另外13个病灶微波治疗后在增强影像中均未见强化,且随着随访时间延长而缩小。结论微波消融对肝脏神经内分泌肿瘤转移病灶是一种安全、有效的非手术治疗手段。

Objective To evaluate the feasibility, safety and efficacy of ultrasound guided microwave （MW） ablation in the treatment of liver metastases of neuroendocrine tumors. Methods Six patients （totally 14 nodules） with liver metastases from neuroendocrine tumors were treated with MW ablation under ultrasourd guidance. The change of the tumor size, contrasted enhanced imagine appearances and the associated complications of MW ablation were observed. Results The technique effective rate was 92.86M （13/14）. One patient had fever, 1 had ache, 1 with tumor adjacent diaphragm had pleural effusion, and the ache induced acute coronary syndrome. One lesion reoccurred 3 months after ablation. The abla- tion zones of the other 13 lesions were well defined on contrast enhanced imaging, and the lesions gradually shrank with time. Conclusion Ultrasound guided MW ablation may be an effective treatment for liver metastases from neuroendocrine tumors.