变应性鼻炎伴腺样体肥大儿童行为调查研究

Behavior research of allergic rhinitis with adenoid hypertrophy in children

目的:探讨变应性鼻炎伴腺样体肥大患儿手术治疗对其行为方面的影响。方法:117例变应性鼻炎伴腺样体肥大患儿随机分成研究组和对照组,其中对照组42例,局部使用类固醇喷鼻剂,连续使用2～3个月,同时给予口服抗组胺药治疗;研究组75例,给予内镜下腺样体切除术,同时使用药物治疗,治疗方法同对照组。3个月后对所有患儿进行行为调查比较,内容包括睡眠、性格、记忆等方面。结果:治疗前两组患儿在腺样体肥大、鼻部症状以及临床问卷分值方面无显著差异,具有可比性。研究组经治疗后在"响鼾"、"不安宁的睡眠或频繁醒觉"、"鼻阻塞而张口呼吸"以及"频繁的上呼吸道感染"4个症状较对照组的改善差异有统计学意义(P<0.05)。结论:变应性鼻炎伴腺样体肥大患儿宜采用手术治疗,腺样体切除利于行为症状的改善。

Objective：To investigate the behavior difference of allergic rhinitis with adenoid hypertrophy be- tween study group and control group. Method： One hundred and seventeen children diagnosed as allergic rhinitis with adenoid hypertrophy were enrolled in our study were divided into study group and control group. Forty-two children treated with local steroid nasal spray for two to three months and antihistamine were control group. Seventy-five children treated with endoscopic adenoidectomy and drug treatment were study group; All children parents were inquired for their clinical presentation. Result： No distinctive differences were found between the two groups（P〉0.05）in adenoid hypertrophy, accompanying nasal problems and clinical questionnaire scoring. Significant statistical distinction were found（P〈0.05）in snoring, sleep disturbance and frequent arousal, nasal obstructive moth-breathing, and recurrent respiratory tract infection between the two groups after three-month follow up. Conclusion：Endoscopic adenoidectomy should he taken into account for allergic rhinitis with adenoid hypertrophy in children. Adenoidectomy would be useful for the improvement of behavior symptoms.