兰州部队精神分裂症发病的危险因素研究

The research on risk factors of schizophrenia in Lanzhou troops

目的 了解部队人群中发生精神分裂症的主要危险因素。方法 应用较规范的病例对照研究方法对 6 6例部队精神分裂症患者及对照进行了危险因素的研究。结果 多因素非条件 L ogistic回归分析筛选出 6个主要危险因素 ,分别是幼年有不良遭遇史 ,精神病家族史 ,发病前与战友关系紧张 ,一年内负性事件评分较高 ,家庭经济差 ,性格中存在明显的精神质。OR及其 95 % CI分别为 3.19(1.0 8～ 9.44 )、191.45 (170 .43～ 2 15 .5 )、2 .93(1.11～ 7.71)、1.18(0 .98～ 1.41)、2 .35 (1.48～3.71)、1.0 7(1.0 1～ 1.41)。结论 部队中精神分裂症的发生是遗传与环境因素共同作用的结果。

Objective To investigate the main risk factors of schizophrenia in troops Method We used a standard case control study method and analysed 66 pairs of subjects Result The multi factorial Logistic analysis showed that poor economical status, misfortune in childhood, family history of psychiatry, tense relationship with colleagues, high P scores of EPQ, the negative life events were risk factors of schizophrenia The ORs were 2 35(1 48～3 71), 3 19(1 08～9 44), 191 45(170 43～215 05), 2 93(1 11～7 71), 1 07(1 01～1 41), 1 18(0 98～11 41), respectively Conclusion The development of schizophrenia was caused by genetic and environmental factors