自拟更健汤联合高压氧治疗围绝经期睡眠障碍的效果观察

The effect of combination Gengjian decoction with hyperbaric oxygen therapy on peri-menopausal dyssomnia

目的观察自拟更健汤联合高压氧治疗妇女围绝经期睡眠障碍的临床效果。方法将60例围绝经期睡眠障碍患者分为治疗组和中药组各30例。中药组给予自拟更健汤;治疗组给予自拟更健汤联合高压氧治疗;随访3个月。观察2组有效率、起效时间及匹兹堡睡眠质量指数(PSQI)的变化。结果治疗组总有效率(93.3%)明显高于中药组(70.0%),差异有统计学意义(P<0.05)。治疗组起效时间短于中药组(6.2 d±2.1 d vs 7.6 d±1.9 d),差异有统计学意义(P<0.05)。治疗组睡眠质量、睡眠时间、睡眠效率、睡眠障碍及PSQI得分均较中药组显著,差异有统计学意义(P<0.05)。结论自拟更健汤联合高压氧治疗能有效地提高围绝经期患者的睡眠质量。

Objective To observe the effect of Gengfian decoction and hyperbaric oxygen therapy on peri-menopausal women with sleep disorders. Methods 60 peri-menopausal women with sleep disorders were divided into treatment group （n = 30） and the traditional Chinese medicine group（ n = 30 ）. Patients in the traditional Chinese medicine group were ad- ministrated with Gengfian decoction, treatment group were administrated with Gengjian decoction together with hyperbaric oxy- gen therapy, following up 3 months. Effective rate, onset time, and the changes of Pittsburgh sleep quality index （PSQI） in two groups were observed. Results The effective rate （93.3%） was higher and the onset time （6.2 d ±2.1 d） was shorter in treatment group than those in traditional Chinese medicine group （70.0% , 7.6 d ± 1.9 d, P 〈0.05）. The PSQI score, sleeping time, sleeping efficiency, dyssomnia improvement were better in treatment group than traditional Chinese medicine group（ P 〈 0.05 ）. Conclusion The Gengfian decoction combined with hyperbaric oxygen therapy could effectively improve sleep quality of peri-menopausal women.