低能量氦氖激光血管内照射对支气管哮喘的疗效及机制研究

The Therapeutic Effect and Mechanism of Low-energy Intravascular He-Ne Laser Irradiation on Bronchial Asthma

目的探讨低能量氦氖激光血管内照射(ILIB)对支气管哮喘的治疗作用及其机制。方法ILIB治疗急性发作期支气管哮喘患者 ,检查临床症状、肺功能、血浆分子物质(MMS)和免疫球蛋白IgG、I gA、IgM含量。结果ILIB治疗后13例哮喘患者症状缓解或减轻,肺功能均不同程度改善,血浆MMS降低,IgG和IgA也明显提高。结论ILIB可作为支气管哮喘的一种有效治疗方法 ,其作用机制可能与降低血浆MMS和自由基含量、增强免疫功能以及改善微循环有关。

Objective To explore the effect and mechanism of intravascular laser irradiation on blood (ILIB) of the patients with bronchial asthma. Methods After being treated with ILIB, the patients with acute bronchial asthma were checked on the change of clinical symptoms, lung function, middle molecular substances (MMS) and immunoglobulins of IgG, IgA and IgM in plasma. Result After being treated with ILIB, the symptoms of 13 patients were controlled or eased, the parameters of lung function were improved to some extent, the content of MMS in plasma reduced and IgG and IgA in plasma increased significantly. Conclusion All these data suggested that ILIB might be an effective method for the treatment of asthma, its mechanism might involve reduction of MMS and free radicals in plasma, enhancement of immunological function and improvement of microcirculation.