摘要
本文采用比色法对甲硝唑注射液降解产物NO_2^-进行测定,找出最佳pH 及灭菌时间,以考察pH 和灭菌时间对甲硝唑降解产物的影响。结果表明,pH=5,灭菌15~30min 甲硝唑降解产物NO_2^-浓度最低。
The degradation of metronidazole in its injection was affected by pH and sterili-zing time.The concentration of the degraded product(NO_2^-)at different pH valuesand differnt sterilizing time was determined by photocolorimetric method.Theexperimental results showed that the pH value 5 and sterilizing time 15~30min,we gained the lowest NO_2^- concentration.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1990年第9期392-394,共3页
Chinese Journal of Hospital Pharmacy